Torsades de pointes following concurrent amiodarone and levofloxacin therapy
Jan Louise Maxa, RPh, Robert Frederick Hebeler, MD, and M. Alade Adeeko, RPh
A case of torsades de pointes is reported following administration of amiodarone concurrent with the fluoroquinolone levofloxacin. Prolongation of the QTc interval has occurred with the fluoroquinolone class of antibiotics. The incidence of torsades has been considered rare with amiodarone. Caution is warranted when these two agents are administered concurrently.
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